Which of the following is a neuroglycopaenic symptom?

• A. Shakiness.
• B. Sweating.
• C. Headache, visual disturbances, mental dullness, confusion, amnesia, seizures, and coma.
• D. Hunger.

Answer: (C)

When blood glucose falls, the brain’s energy supply is the first to become critically depleted, leading to neuroglycopenic symptoms. These reflect impaired brain function from lack of glucose and include headache, visual disturbances, mental dullness, confusion, amnesia, seizures, and coma. They show up as the brain’s cognitive and neurologic abilities falter due to energy failure.

Shakiness, sweating, and hunger, by contrast, come from autonomic counterregulation—release of catecholamines like adrenaline in response to falling glucose. These are early, adrenergic signs rather than signs of brain energy deficiency, so they don’t represent neuroglycopenia.