Which of the following is an example of an antiplatelet?

• A. Ibuprofen
• B. Furosemide
• C. Metformin
• D. Aspirin, clopidogrel, ticagrelor, prasugrel

Answer: (D)

Antiplatelet drugs prevent platelets from sticking together to form clots in arteries. Aspirin works by irreversibly inhibiting COX-1 in platelets, which lowers thromboxane A2 and reduces platelet aggregation. The other drugs listed are P2Y12 inhibitors (clopidogrel, ticagrelor, prasugrel) that block the P2Y12 receptor on platelets, preventing ADP-mediated activation and further platelet clumping. Together, these agents are classic antiplatelet therapy.

Ibuprofen is an NSAID that can transiently affect platelet function but isn’t classified as an antiplatelet therapy. Furosemide is a diuretic, and metformin is an antidiabetic agent. Therefore, the group that includes aspirin and the P2Y12 inhibitors is the example of an antiplatelet.