Which of the following is a contraindication to beta-blockers?

• A. Hypertension
• B. Asthma
• C. Hyperlipidemia
• D. Age over 65

Answer: (B)

The idea here is understanding why beta-blockers are avoided in certain lung conditions. Beta-blockers block beta-adrenergic receptors, which helps lower heart rate and blood pressure, but they can also block the beta-2 receptors in the airways. When these receptors are blocked, the airways can constrict, making breathing harder. In someone with asthma, this bronchoconstriction can provoke a dangerous asthma attack, so beta-blockers are typically avoided or used with extreme caution, especially non-selective ones that block both beta-1 and beta-2 receptors.

Hypertension is actually an indication for beta-blockers, not a contraindication. Hyperlipidemia isn’t a contraindication either, and while age over 65 means you’ll watch for other health issues, it isn’t by itself a reason to avoid beta-blockers.