Which of the following is a sensory symptom commonly associated with CIPN?

• A. Hearing loss
• B. Dizziness
• C. Numbness
• D. Shortness of breath

Answer: (C)

Chemotherapy-induced peripheral neuropathy involves damage to the peripheral nerves, leading to sensory changes in the extremities. Numbness is a classic sensory symptom because it reflects a loss or reduction of sensation in the skin and deeper tissues, often in a stocking-glove pattern in hands and feet. This type of neuropathy commonly presents with numbness, tingling, or burning sensations as the nerves’ ability to transmit normal sensory information is impaired.

Hearing loss would point to ototoxicity affecting the ear’s structures, not primarily the peripheral nerves. Dizziness can arise from many issues, including vestibular or circulatory problems, and shortness of breath points to cardiopulmonary or systemic concerns rather than a peripheral nerve sensory issue. Among these options, numbness best fits the sensory symptom profile of CIPN.