Which of the following is NOT an absolute contraindication to ACE inhibitors or ARBs?

• A. Pregnancy
• B. Angioedema
• C. Hyperkalaemia
• D. Diabetes mellitus

Answer: (D)

The key idea is recognizing true contraindications to ACE inhibitors or ARBs. Pregnancy is an absolute contraindication because these drugs can cause fetal harm. A history of angioedema with these medications is a major safety concern due to the risk of life-threatening swelling, so they’re not used. Hyperkalemia is dangerous with these drugs since potassium can rise to dangerous levels, making it another absolute contraindication. Diabetes mellitus is not an absolute barrier; in fact, ACE inhibitors and ARBs are commonly used in diabetics to control blood pressure and protect kidney function, with careful monitoring of potassium and kidney performance.