What percentage weight loss is typically observed with higher-dose GLP-1 receptor agonists like Ozempic and Saxenda?

• A. 2-3%
• B. 6-8%
• C. 4-5%
• D. 9-12%

Answer: (C)

GLP-1 receptor agonists help with weight loss by lowering appetite, increasing fullness, and slowing stomach emptying. When used at higher doses like semaglutide (Ozempic) and liraglutide (Saxenda), the typical weight reduction seen is about 4-5% of starting weight after several months. This reflects a meaningful but modest effect compared with larger losses seen at the highest obesity-specific doses of semaglutide. Individual results vary with how long you use the medication, adherence, and baseline weight.