Germ cell tumours are tumours arising from which cells, commonly located where?

• A. Reproductive cells; commonly in testes and ovaries
• B. Pigment lesions
• C. Brain tissue
• D. Lymphoid tissue

Answer: (A)

Germ cell tumors come from the cells that give rise to sperm in males and eggs in females. Because these cells reside mainly in the gonads, germ cell tumors are most commonly found in the testes and ovaries. There can be tumors in other midline areas when germ cells migrate abnormally, but the usual and most common location is the gonads. The other options point to different cell lineages—pigment-producing melanocytes, brain neural tissue, and lymphoid immune cells—not germ cells.